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1

Genomic organization of the flt-1 gene encoding for Vascular Endothelial Growth Factor (VEGF) Receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors

Kunio Kondo, Sachie Hiratsuka, Easwaran Subbalakshmi, Hitoshi Matsushime, Masabumi Shibuya

Journal:

Year:

1998

Language:

english

File:

PDF, 686 KB

english, 1998

2

The Phosphorylated 1169-Tyrosine Containing Region of Flt-1 Kinase (VEGFR-1) Is a Major Binding Site for PLCγ

Asako Sawano, Tomoko Takahashi, Sachiko Yamaguchi, Masabumi Shibuya

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 884 KB

english, 1997

3

[Advances in Cancer Research] Volume 67 || Role of Vegf-Flt Receptor System in Normal and Tumor Angiogenesis

Shibuya, Masabumi

Year:

1995

Language:

english

File:

PDF, 1.95 MB

english, 1995

4

The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions

Takahashi, Hiroyuki, Shibuya, Masabumi

Journal:

Clinical Science

Year:

2005

Language:

english

File:

PDF, 409 KB

english, 2005

5

In situ localization of male germ cell-associated kinase (mak) mRNA in adult mouse testis: Specific expression in germ cells at stages around meiotic cell division

Dr Takehiko Koji, Atsushi Jinno, Hitoshi Matsushime, Masabumi Shibuya, Paul K. Nakane

Journal:

Cell Biochemistry and Function

Year:

1992

Language:

english

File:

PDF, 1.64 MB

english, 1992

6

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

Hiratsuka, Sachie, Watanabe, Akira, Sakurai, Yoshiko, Akashi-Takamura, Sachiko, Ishibashi, Sachie, Miyake, Kensuke, Shibuya, Masabumi, Akira, Shizuo, Aburatani, Hiroyuki, Maru, Yoshiro

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 2.86 MB

english, 2008

7

Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)

Masabumi Shibuya

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2001

Language:

english

File:

PDF, 405 KB

english, 2001

8

Vascular Endothelial Growth Factor (VEGF)-Receptor2: Its Biological Functions, Major Signaling Pathway, and Specific Ligand VEGF-E

Shibuya, Masabumi

Journal:

Year:

2006

Language:

english

File:

PDF, 855 KB

english, 2006

9

The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina

Luft, Veronika, Reinhard, Jacqueline, Shibuya, Masabumi, Fischer, Klaus D., Faissner, Andreas

Journal:

Cell and Tissue Research

Year:

2015

Language:

english

File:

PDF, 11.52 MB

english, 2015

10

Erratum to: The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina

Luft, Veronika, Reinhard, Jacqueline, Shibuya, Masabumi, Fischer, Klaus D., Faissner, Andreas

Journal:

Cell and Tissue Research

Year:

2015

Language:

english

File:

PDF, 4.14 MB

english, 2015

11

Lymphangiogenesis induced by vascular endothelial growth factor receptor 1 signaling contributes to the progression of endometriosis in mice

Hattori, Kyoko, Ito, Yoshiya, Honda, Masako, Sekiguchi, Kazuki, Hosono, Kanako, Shibuya, Masabumi, Unno, Nobuya, Majima, Masataka

Journal:

Journal of Pharmacological Sciences

Year:

2020

File:

PDF, 2.81 MB

2020

12

Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1show vascular endothelial growth factor expression

Hitoshi Yoshiji, Steven R. Harris, Erzsebet Raso, Daniel E. Gomez, Carol K. Lindsay, Masabumi Shibuya, Constance C. Sinha, Unnur P. Thorgeirsson

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 482 KB

english, 1998

13

Virally activated ras cooperates with integrin to induce tubulogenesis in sinusoidal endothelial cell lines

Yoshiro Maru, Sachiko Yamaguchi, Tomoko Takahashi, Hikaru Ueno, Masabumi Shibuya

Journal:

Journal of Cellular Physiology

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

14

Undetectable bcr-abl rearrangements in some CML patients are due to a deletion mutation in the bcr gene

Shinsaku Hirosawa, Nobuo Aoki, Hitoshi Matsushime, Masabumi Shibuya

Journal:

American Journal of Hematology

Year:

1988

Language:

english

File:

PDF, 331 KB

english, 1988

15

Tumor-infiltrating endothelial cells and endothelial precursor cells in inflammatory breast cancer

Kazuo Shirakawa, Masabumi Shibuya, Yuji Heike, Shigemitsu Takashima, Ichiro Watanabe, Fumio Konishi, Fujio Kasumi, Corey K. Goldman, Kenneth A. Thomas, Andrew Bett, Masaaki Terada, Hiro Wakasugi

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 4.22 MB

english, 2002

16

Structural abnormality and over-expression of the myc gene in feline leukemias

Tomoluki Miura, Hajime Tsujimoto, Masashi Fukasawa, Toshiaki Kodama, Masabumi Shibuya, Atsuhiko Hasegawa, Masanori Hayami

Journal:

International Journal of Cancer

Year:

1987

Language:

english

File:

PDF, 1.15 MB

english, 1987

17

Increase of vascular endothelial growth factor mRNA expression by 1,25-dihydroxyvitamin D3 in human osteoblast-like cells

Da Shen Wang, Kazuko Yamazaki, Kyoko Nohtomi, Kazuo Shizume, Kazuoki Ohsumi, Masabumi Shibuya, Hiroshi Demura, Dr. Kanji Sato

Journal:

Journal of Bone and Mineral Research

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

18

Expression of vascular endothelial growth factor receptors in smooth muscle cells

Atsushi Ishida, Jacqueline Murray, Yuji Saito, Chryso Kanthou, Omar Benzakour, Masabumi Shibuya, Errol S. Wijelath

Journal:

Journal of Cellular Physiology

Year:

2001

Language:

english

File:

PDF, 329 KB

english, 2001

19

A suppressive effect of an Epstein-Barr virus-immortalized cell line on leukemic cells

Yoshitora Kin, Masabumi Shibuya, Yoshiro Maru

Journal:

Clinical Biochemistry

Year:

2001

Language:

english

File:

PDF, 1.91 MB

english, 2001

20

An FGF4-FRS2α-Cdx2 Axis in Trophoblast Stem Cells Induces Bmp4 to Regulate Proper Growth of Early Mouse Embryos

Michiko Murohashi, Takahisa Nakamura, Satoshi Tanaka, Taeko Ichise, Nobuaki Yoshida, Tadashi Yamamoto, Masabumi Shibuya, Joseph Schlessinger, Noriko Gotoh

Journal:

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

21

Transcription of theE. coli tufBgene: Cotranscription with four tRNA genes and inhibition by guanosine-5′-diphosphate-3′-diphosphate

Atsushi Miyajima, Masabumi Shibuya, Yoshiyuki Kuchino, Yoshito Kaziro

Journal:

Molecular Genetics and Genomics

Year:

1981

Language:

english

File:

PDF, 771 KB

english, 1981

22

Cloning of anEcoRI fragment carryingE. coli tufAgene

Masabumi Shibuya, Hiroko Nashimoto, Yoshito Kaziro

Journal:

Molecular Genetics and Genomics

Year:

1979

Language:

english

File:

PDF, 427 KB

english, 1979

23

A novel low molecular weight VEGF receptor-binding antagonist, VGA1102, inhibits the function of VEGF and in vivo tumor growth

Yasuji Ueda, Takehiro Yamagishi, Kazunori Samata, Hisao Ikeya, Noriko Hirayama, Tadayasu Okazaki, Sumi Nishihara, Koshi Arai, Sachiko Yamaguchi, Masabumi Shibuya, Shiro Nakaike, Makoto Tanaka

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 1.62 MB

english, 2004

24

Involvement of VEGF and its receptors in ascites tumor formation

Masabumi Shibuya, Jin-Cai Luo, Masashi Toyoda, Sachiko Yamaguchi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

25

Inhibition of choroidal neovascularization by blocking vascular endothelial growth factor receptor tyrosine kinase

Junko Kami, Kimimasa Muranaka, Yasuo Yanagi, Ryo Obata, Yasuhiro Tamaki, Masabumi Shibuya

Journal:

Japanese Journal of Ophthalmology

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

26

Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model

Sandra R. Brave, Cath Eberlein, Masabumi Shibuya, Stephen R. Wedge, Simon T. Barry

Journal:

Year:

2010

Language:

english

File:

PDF, 390 KB

english, 2010

27

Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases

Hiroyuki Nakamura, Yusuke Sasaki, Masaharu Uno, Tomohiro Yoshikawa, Toru Asano, Hyun Seung Ban, Hidesuke Fukazawa, Masabumi Shibuya, Yoshimasa Uehara

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

28

Isolation and Characterization of cDNA for an Androgen-Regulated mRNA in the Flank Organ of Hamsters.

Seki, Toshihiko, Ideta, Ritsuro, Shibuya, Masabumi, Adachi, Kenji

Journal:

The Journal of Investigative Dermatology

Year:

1991

File:

PDF, 2.37 MB

1991

29

Co-amplification of c-myc and c-erbB-2 Oncogenes in a Poorly Differentiated Human Gastric Cancer

Terumasa Tsuchiya, Yoshito Ueyama, Norikazu Tamaoki, Sachiko Yamaguchi, Masabumi Shibuya

Journal:

Year:

1989

File:

PDF, 238 KB

1989

30

Alterations of Mouse Proto-oncogenes in Sarcomas Induced after Transplantation of Human Tumors in Athymic Nude Mice

Yasuhito Yuasa, Hitoshi Yamazaki, Kohji Maruo, Yoshito Ueyama, Masabumi Shibuya, Norikazu Tamaoki

Journal:

Year:

1990

File:

PDF, 493 KB

1990

31

A Deletion Mutation within the Ligand Binding Domain Is Responsible for Activation of Epidermal Growth Factor Receptor Gene in Human Brain Tumors

Hitoshi Yamazaki, Yoshito Ohba, Norikazu Tamaoki, Masabumi Shibuya

Journal:

Year:

1990

File:

PDF, 425 KB

1990

32

Establishment of a Human Small Cell Lung Carcinoma Cell Line Carrying Amplification of c-myc Gene and Chromosomal Translocation of t(3p;6p) and t(12q;17p)

Atsushi Kato, Takashi Kamiyama, Sachiko Yamaguchi, Katsuko Sudo, Shigeo Mori, Morimasa Sekiguchi, Nobuo Aoki, Masabumi Shibuya

Journal:

Year:

1993

File:

PDF, 241 KB

1993

33

Characterization of the Promoter Region of the Human c-kit Proto-oncogene

Katsuya Yamamoto, Arinobu Tojo, Nobuo Aoki, Masabumi Shibuya

Journal:

Year:

1993

File:

PDF, 794 KB

1993

34

Characterization of the Extracellular Domain in Vascular Endothelial Growth Factor Receptor-1 (Flt-1 Tyrosine Kinase)

Keiji Tanaka, Sachiko Yamaguchi, Asako Sawano, Masabumi Shibuya

Journal:

Year:

1997

File:

PDF, 648 KB

1997

35

Clotrimazole, an Imidazole Antimycotic, Is a Potent Inhibitor of Angiogenesis

Hiroto Takahashi, Mayumi Abe, Toshiyuki Sugawara, Katsuhiro Tanaka, Yasuki Saito, Sigefumi Fujimura, Masabumi Shibuya, Yasufumi Sato

Journal:

Year:

1998

Language:

english

File:

PDF, 659 KB

english, 1998

36

Expression of Vascular Endothelial Growth Factor and E-Cadherin in Human Ovarian Cancer: Association with Ascites Fluid Accumulation and Peritoneal Dissemination in Mouse Ascites Model

Noriyuki Akutagawa, Akira Nishikawa, Masahiro Iwasaki, Takashi Fujimoto, Mizue Teramoto, Yoshimitsu Kitajima, Toshiaki Endo, Masabumi Shibuya, Ryuichi Kudo

Journal:

Year:

2002

Language:

english

File:

PDF, 649 KB

english, 2002

37

β-Hydroxyisovalerylshikonin Is a Novel and Potent Inhibitor of Protein Tyrosine Kinases

Sachiko Hashimoto, Ying Xu, Yutaka Masuda, Toshihiro Aiuchi, Shigeo Nakajo, Yoshimasa Uehara, Masabumi Shibuya, Takao Yamori, Kazuyasu Nakaya

Journal:

Year:

2002

Language:

english

File:

PDF, 641 KB

english, 2002

38

Induction of tube formation by angiopoietin-1 in endothelial cell/fibroblast co-culture is dependent on endogenous VEGF

Momomi Saito, Maho Hamasaki, Masabumi Shibuya

Journal:

Year:

2003

Language:

english

File:

PDF, 1.80 MB

english, 2003

39

Vascular endothelial growth factor receptor-2: Its unique signaling and specific ligand, VEGF-E

Masabumi Shibuya

Journal:

Year:

2003

Language:

english

File:

PDF, 2.55 MB

english, 2003

40

Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle

Mai Yamauchi, Shinobu Imajoh-Ohmi, Masabumi Shibuya

Journal:

Year:

2007

Language:

english

File:

PDF, 431 KB

english, 2007

41

Anti-tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model

Eri Taguchi, Kazuhide Nakamura, Toru Miura, Masabumi Shibuya, Toshiyuki Isoe

Journal:

Year:

2008

Language:

english

File:

PDF, 454 KB

english, 2008

42

Mechanism of inhibition of tumor angiogenesis by β-hydroxyisovalerylshikonin

Yusuke Komi, Yasuhiro Suzuki, Mariko Shimamura, Sachiko Kajimoto, Shigeo Nakajo, Michitaka Masuda, Masabumi Shibuya, Hiroyuki Itabe, Kentaro Shimokado, Peter Oettgen, Kazuyasu Nakaya, Soichi Kojima

Journal:

Year:

2009

Language:

english

File:

PDF, 598 KB

english, 2009

43

Hypoxia and low-nutrition double stress induces aggressiveness in a murine model of melanoma

Tsuyoshi Osawa, Masashi Muramatsu, Makoto Watanabe, Masabumi Shibuya

Journal:

Year:

2009

Language:

english

File:

PDF, 2.66 MB

english, 2009

44

Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis

Feng Wang, Tsuyoshi Osawa, Rika Tsuchida, Yasuhito Yuasa, Masabumi Shibuya

Journal:

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

45

Regulation of clathrin-mediated endocytosis by p53

Yoshie Endo, Atsumi Sugiyama, Shun-Ai Li, Kazuji Ohmori, Hirokazu Ohata, Yusuke Yoshida, Masabumi Shibuya, Kohji Takei, Masato Enari, Yoichi Taya

Journal:

Year:

2008

Language:

english

File:

PDF, 873 KB

english, 2008

46

Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor

Masabumi Shibuya

Journal:

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

47

Properties of Two VEGF Receptors, Flt-1 and KDR, in Signal Transduction

YASUFUMI SATO, SHINICHI KANNO, NOBUYUKI ODA, MAYUMI ABE, MIKITO ITO, KENYA SHITARA, MASABUMI SHIBUYA

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

48

Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1

Fukuhara, Shigetomo, Sako, Keisuke, Minami, Takashi, Noda, Kazuomi, Kim, Hak Zoo, Kodama, Tatsuhiko, Shibuya, Masabumi, Takakura, Nobuyuki, Koh, Gou Young, Mochizuki, Naoki

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 6.95 MB

english, 2008

49

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1

Sasaki, Atsuo, Taketomi, Takaharu, Kato, Reiko, Saeki, Kazuko, Nonami, Atsushi, Sasaki, Mika, Kuriyama, Masamitsu, Saito, Naoaki, Shibuya, Masabumi, Yoshimura, Akihiko

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 2.21 MB

english, 2003

50

Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein

Usui, Ryosuke, Shibuya, Masabumi, Ishibashi, Shun, Maru, Yoshiro

Journal:

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

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